Generic Aricept (Donepezil 5/10mg) 1. Denomination
Aricept
2. Active Substance
Donepezil Hcl
3. Indications for Use.
Breaking of the mental functions as consequence of brain lesion, predominantly in old age. Alzheimer disease (of light and medium severity level) in adults, including elderly ones (symptomatic treatment).
4. Action
Donepezil Hcl slows down the progression of Alzheimer, reduces the manifestation of symptoms, in some cases restores diurnal activity of patients and facilitates the care. The drug corrects behavioral disorders: apathy, hallucinations and non-conscious repeated motions.
5. Posology and Administration
The therapy should be ordered and administered by a doctor experienced in Alzheimer disease.
Adults (including elderly age patients) should be administered as an initial dose 5 mg once/daily. Administration in the initial dose should be continued during not less than 4-6 weeks in order to reach equilibrium concentrations of Donepezil Hcl and to determine an early clinical effect of the therapy. After 1 month a dose may be increased up to 10 mg/daily.
The maximal dose is 10 mg/daily.
A supporting therapy may be continued till the therapeutic effect is preserved, which should be assessed regularly.
6. Counterindications
Donepezil Hcl is counterindicated in pregnancy and in lactation period, in children before 18 years of age, sufferers of muscle activity disorders, of breathing organs, arrhythmia, ulcer and duodenal disease patients, likewise in the patients with individual intolerance of Donepezil Hcl and its compounds.
7. Should Be Taken with Precautions, if…
The treatment should be started and continued under the control of a medical specialist and having an appropriate sicknursing (control drug administration control etc.). It is impossible to predict Donepezil Hcl therapy individual response. Сare should be taken in administration when there are concomitant arrythmias, ulcer disease, bronchial asthma and other lungs diseases.
For the period of the treatment alcohol consumption should be avoided.
8. Interface with Other Medications
During Donepezil Hcl therapy the risk of the unknown till present time manifestations of intercourse with other drugs, and in all the matters that you are interested, please, consult your doctor.
9. Overdosing
Symotoms: evidenced nausea, vomit, salivation, elevated perspiration, bradycardia, decrease of arterial tension, respiratory depression, near death condition, convulsions. Development of the rapid fatigability of muscles which is likely to result in lethal outcome in case of the damage of respiratory muscles.
10. Side Effects
Nausea, vomit, dyspepsia, diarrhea, headache, dizziness, increased fatigability, insomnia, faintness, heartbeat disorder, muscle convulsions; hallucinations, qualms, aggressive behavior, epileptic fits. Blood compositional disorder.
11. Pregnancy and Lactation
Donepezil Hcl is prohibited to administer in the period of pregnancy, also it is prohibited to be administered during breastfeeding.
12. Driving
The possibility of vehicle driving and sophisticated machinery while using Donepezil Hcl should be assessed by a medical specialist only.
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