Generic Aciphex

1. Denomination

Aciphex

2. Active Substance

Raberprazole Sodium

3. Indications for Use.

-  gastric ulcer and duodenal ulcer in a recrudescence phase;
-  gastric ulcer and duodenal ulcer associated with Helicobacter pylori (helicobacteriosis of gastric-intestinal tract);
-  gastroesophageal reflux, reflux-esophagitis;
-  Zollinger-Ellison syndrome;
-  stress ulcers of gastric-intestinal tract.

4. Action

Raberprazole Sodium provokes an evidenced and long-term reduction of hydrochloric acid formation.

5. Posology and Administration

Raberprazole Sodium should be taken in the morning, before meal, without chewing, and without crushing; when there is gastric ulcer in a recrudescence stage it should be taken 20 mg once a day during 4 weeks, when there is insufficient adhesion – an additional treatment should be taken for 4 weeks more; when there is duodenal ulcer it should be taken 10 or 20 mg once daily during 6 weeks, when there is insufficient adhesion an additional treatment should be taken for 6 weeks more; when there is gastroesophageal reflux disease it should be taken 20 mg once daily during 4–8 weeks, further on it is possible a supporting therapy: 10–20 mg once a day. When there is infection H. pylori (within a triple combined therapy) — Raberprazole Sodium 20 mg each twice a day in combination with clarithromycin 500 mg/a day and amoxicillin 1000 mg/a day during 7 days.

6. Counterindications

Hypersensitivity, pregnancy, lactation period. Precaution should be taken when there is childhood and liver failure.

7. Should Be Taken with Precautions, if…

Before the beginning of the treatment it is necessary to exclude malignant neoplasms of the stomach. It is recommended to exercise caution in the first administration of Raberprazole Sodium to the patients with severe compromised liver function.
Raberprazole Sodium is not recommended to administer in children, because nowadays there is no experience of its use in pediatrics.

8. Interface with Other Medications

In the time of necessity to take Raberprazole Sodium within a combined therapy take to heart recommendations of your attending doctor on this matter.

9. Overdosing

There is no information on overdosage of Raberprazole Sodium nowadays. Administration of this drug in a dose of 80 mg/a day did not result in the development of any life threatening symptoms.

10. Side Effects

On the part of GIT organs: diarrhea, nausea; less often – vomiting, pain in the stomach, constipation; seldom – dry mouth, belching, in isolated cases – taste disturbances, anorexia, stomatitis, gastritis.
On the part of nervous system and sense bodies: headache; less often — dizziness, insomnia; very seldom — nervousness, drowsiness; in separate cases — depression, vision disorders.
On the part of locomotor apparatus: pains in legs, convulsions of calves.

11. Pregnancy and Lactation

Raberprazole Sodium is counterindicated for the use in pregnancy, owing to the absence of the accurate clinic data which may confirm the safety of the use of this drug in this period. If there is a need to use Raberprazole Sodium in lactation period a question should be decided on cessation of breastfeeding (due to the absence of data on excretion of Raberprazole Sodium with breast milk).

12. Driving

On the basis of the characteristics of Raberprazole Sodium and side effects it is not likely that the drug has influence on the ability to drive vehicles and operate machinery. But in the case of emerging drowsiness these kinds of activities should be avoided.

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Q. Can you tell me if I should be taking Generic Aciphex ( Rabeprazole sodium 20mg ) ? Or, will it work for me?
A. We cannot advise you in any capacity in this matter. You should not take any medication without consulting a physician first.

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A. By law, we regret that we are unable to accept returned pharmaceuticals. If your purchase is defective in any way, we will be pleased to replace it at no cost to you.

Q. What about importing of Generic Aciphex ( Rabeprazole sodium 20mg ) to my country ?
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